The way I see it is this:
How much further along toward revitalization would we be if one-way streets weren't working against our efforts, 24/7/365?
ONE-WAY TO KILL YOUR DOWNTOWN RETAIL, by Jason Schaeffer (Strong Towns)
We talk a lot at Strong Towns about how a street designed around automobiles with little regard for people has an assortment of negative consequences. One of them is economic vitality. Particularly for store fronts in downtowns with a stroad running past them.